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Latent Epstein-Barr Virus Can Inhibit Apoptosis in B Cells by Blocking the Induction of NOXA Expression

Latent Epstein-Barr virus (EBV) has been shown to protect Burkitt's lymphoma-derived B cells from apoptosis induced by agents that cause damage to DNA, in the context of mutant p53. This protection requires expression of the latency-associated nuclear proteins EBNA3A and EBNA3C and correlates w...

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Detalhes bibliográficos
Main Authors: Yee, Jade, White, Robert E., Anderton, Emma, Allday, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235132/
https://ncbi.nlm.nih.gov/pubmed/22174825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028506
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