Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index

Background Cigarette smoking is associated with lower body mass index (BMI), and a commonly cited reason for unwillingness to quit smoking is a concern about weight gain. Common variation in the CHRNA5-CHRNA3-CHRNB4 gene region (chromosome 15q25) is robustly associated with smoking quantity in smoke...

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Main Authors: Freathy, Rachel M, Kazeem, Gbenga R, Morris, Richard W, Johnson, Paul C D, Paternoster, Lavinia, Ebrahim, Shah, Hattersley, Andrew T, Hill, Anita, Hingorani, Aroon D, Holst, Claus, Jefferis, Barbara J, Kring, Sofia I I, Mooser, Vincent, Padmanabhan, Sandosh, Preisig, Martin, Ring, Susan M, Sattar, Naveed, Upton, Mark N, Vollenweider, Peter, Waeber, Gerard, Sørensen, Thorkild I A, Frayling, Timothy M, Watt, Graham, Lawlor, Debbie A, Whincup, Peter H, Tozzi, Federica, Davey Smith, George, Munafò, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Genetic Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235017/
https://ncbi.nlm.nih.gov/pubmed/21593077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyr077
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