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Ligand Specificity Determined by Differentially Arranged Common Ligand-binding Residues in Bacterial Amino Acid Chemoreceptors Tsr and Tar

Escherichia coli has closely related amino acid chemoreceptors with distinct ligand specificity, Tar for l-aspartate and Tsr for l-serine. Crystallography of the ligand-binding domain of Tar identified the residues interacting with aspartate, most of which are conserved in Tsr. However, swapping of...

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Detalhes bibliográficos
Main Authors: Tajima, Hirotaka, Imada, Katsumi, Sakuma, Mayuko, Hattori, Fumiyuki, Nara, Toshifumi, Kamo, Naoki, Homma, Michio, Kawagishi, Ikuro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234949/
https://ncbi.nlm.nih.gov/pubmed/21979954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.221887
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