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Endogenous Myoglobin in Breast Cancer Is Hypoxia-inducible by Alternative Transcription and Functions to Impair Mitochondrial Activity: A ROLE IN TUMOR SUPPRESSION?
Recently, immunohistochemical analysis of myoglobin (MB) in human breast cancer specimens has revealed a surprisingly widespread expression of MB in this nonmuscle context. The positive correlation with hypoxia-inducible factor 2α (HIF-2α) and carbonic anhydrase IX suggested that oxygen regulates my...
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Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2011
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234873/ https://ncbi.nlm.nih.gov/pubmed/21930697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.227553 |
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