Native Thrombocidin-1 and Unfolded Thrombocidin-1 Exert Antimicrobial Activity via Distinct Structural Elements

Chemokines (chemotactic cytokines) can have direct antimicrobial activity, which is apparently related to the presence of a distinct positively charged patch on the surface. However, chemokines can retain antimicrobial activity upon linearization despite the loss of their positive patch, thus questi...

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Autori principali: Kwakman, Paulus H. S., Krijgsveld, Jeroen, de Boer, Leonie, Nguyen, Leonard T., Boszhard, Laura, Vreede, Jocelyne, Dekker, Henk L., Speijer, Dave, Drijfhout, Jan W., te Velde, Anje A., Crielaard, Wim, Vogel, Hans J., Vandenbroucke-Grauls, Christina M. J. E., Zaat, Sebastian A. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234844/
https://ncbi.nlm.nih.gov/pubmed/22025617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248641
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