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Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells.

A retrovirus-derived vector called self-inactivating (SIN) vector was designed for the transduction of whole genes into mammalian cells. SIN vectors contain a deletion of 299 base pairs in the 3' long terminal repeat (LTR), which includes sequences encoding the enhancer and promoter functions. When...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Yu, S F, von Rüden, T, Kantoff, P W, Garber, C, Seiberg, M, Rüther, U, Anderson, W F, Wagner, E F, Gilboa, E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323479/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.10.3194
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