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Two-component PhoB-PhoR Regulatory System and Ferric Uptake Regulator Sense Phosphate and Iron to Control Virulence Genes in Type III and VI Secretion Systems of Edwardsiella tarda

Inorganic phosphate (P(i)) and iron are essential nutrients that are depleted by vertebrates as a protective mechanism against bacterial infection. This depletion, however, is sensed by some pathogens as a signal to turn on the expression of virulence genes. Here, we show that the PhoB-PhoR two-comp...

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Detalhes bibliográficos
Main Authors: Chakraborty, Smarajit, Sivaraman, J., Leung, Ka Yin, Mok, Yu-Keung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234765/
https://ncbi.nlm.nih.gov/pubmed/21953460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.295188
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