No Mutations of Lysophosphatidic Acid Receptor Genes in Lung Adenocarcinomas Induced by N-Nitrosobis(2-hydroxypropyl)amine in Rats

Lysophosphatidic acid (LPA) is a bioactive phospholipid that stimulates cell proliferation and migration, and protects cells from apoptosis. It interacts with specific G protein-coupled transmembrane receptors. Recently, frequent mutations of the LPA receptor-1 (LPA1) gene were detected in rat lung...

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Detalhes bibliográficos
Main Authors: Wakabayashi, Naoko, Tsujino, Megumu, Tajiri, Masaki, Taki, Midori, Koshino, Ayumi, Ikeda, Hiroko, Fukushima, Nobuyuki, Tsujiuchi, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Toxicologic Pathology 2010
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234649/
https://ncbi.nlm.nih.gov/pubmed/22272013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.23.63
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