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Extraskeletal Osteosarcoma with Pulmonary Metastasis in a Female F344 Rat

A subcutaneous mass in the right femoral region of a female F344 Slc/N rat was examined histopathologically. At 83 weeks of age, the animal showed symptoms of severe anemia and nasal bleeding. Necropsy revealed that the mass had invaded the skeletal muscles but did not affect the bones. Multicentric...

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Detalhes bibliográficos
Main Authors: Nagaike, Mika, Sakai, Kimie, Tsuchiya, Seiichiro, Shimada, Fumi, Inui, Kosei, Uratani, Mamoru
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Toxicologic Pathology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234624/
https://ncbi.nlm.nih.gov/pubmed/22272046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.24.75
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