A mutation that prevents glucosylation of the lipid-linked oligosaccharide precursor leads to underglycosylation of secreted yeast invertase.

A mutant of Saccharomyces cerevisiae with the genotype mnn1 mnn2 mnn9 gls1 synthesizes mannoproteins with oligosaccharides having the composition Glc3Man10Glc-NAc2- owing to the mnn9 defect, which prevents synthesis of the outer chain, the mnn1 defect, which prevents branching of the core, and the g...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ballou, L, Gopal, P, Krummel, B, Tammi, M, Ballou, C E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323456/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3517849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.10.3081
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