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Loss of perforated synapses in the dentate gyrus: morphological substrate of memory deficit in aged rats.

Most, but not all, aged rats exhibit a profound deficit in spatial memory when tested in a radial maze--a task known to depend on the integrity of the hippocampal formation. In this study, animals were divided into three groups based on their spatial memory capacity: young adult rats with good memor...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Geinisman, Y, de Toledo-Morrell, L, Morrell, F
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458260/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.9.3027
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