Skeletal Muscle-Specific Expression of PGC-1α-b, an Exercise-Responsive Isoform, Increases Exercise Capacity and Peak Oxygen Uptake

BACKGROUND: Maximal oxygen uptake (VO(2max)) predicts mortality and is associated with endurance performance. Trained subjects have a high VO(2max) due to a high cardiac output and high metabolic capacity of skeletal muscles. Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a nu...

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Autores principales: Tadaishi, Miki, Miura, Shinji, Kai, Yuko, Kano, Yutaka, Oishi, Yuichi, Ezaki, Osamu
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234261/
https://ncbi.nlm.nih.gov/pubmed/22174785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028290
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