The effect of the CCR5-delta32 deletion on global gene expression considering immune response and inflammation

BACKGROUND: The natural function of the C-C chemokine receptor type 5 (CCR5) is poorly understood. A 32 base pair deletion in the CCR5 gene (CCR5-delta32) located on chromosome 3 results in a non-functional protein. It is supposed that this deletion causes an alteration in T-cell response to inflamm...

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Библиографические подробности
Главные авторы: Hütter, Gero, Neumann, Martin, Nowak, Daniel, Klein, Stefan, Klüter, Harald, Hofmann, Wolf-K
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234179/
https://ncbi.nlm.nih.gov/pubmed/22029606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-8-29
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