Testosterone allosterically regulates ethanol oxidation by homo- and heterodimeric gamma-subunit-containing isozymes of human alcohol dehydrogenase.

Testosterone and its physiologically active metabolite 5 alpha-dihydrotestosterone are selective, allosteric inhibitors of the gamma subunit-containing isozymes of class I human alcohol dehydrogenase (ADH) with apparent Ki values for testosterone at pH 7.4 between 3.5 and 16 X 10(-6) M. Testosterone...

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Main Authors: Mårdh, G, Falchuk, K H, Auld, D S, Vallee, B L
Format: Artigo
Jezik:Inglês
Izdano: 1986
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC323401/
https://ncbi.nlm.nih.gov/pubmed/2939458
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