Increased renin excretion is associated with augmented urinary angiotensin II levels in chronic angiotensin II-infused hypertensive rats

Renin expression in principal cells of collecting ducts (CD) is upregulated in angiotensin II (ANG II)-dependent hypertensive rats; however, it remains unclear whether increased CD-derived renin undergoes tubular secretion. Accordingly, urinary levels of renin (uRen), angiotensinogen (uAGT), and ANG...

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Detalhes bibliográficos
Main Authors: Liu, Liu, Gonzalez, Alexis A., McCormack, Michael, Seth, Dale M., Kobori, Hiroyuki, Navar, L. Gabriel, Prieto, Minolfa C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Editorial Focus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233871/
https://ncbi.nlm.nih.gov/pubmed/21865264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00339.2011
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