Human microvascular dysfunction and apoptotic injury induced by AL amyloidosis light chain proteins

Light chain amyloidosis (AL) involves overproduction of amyloidogenic light chain proteins (LC) leading to heart failure, yet the mechanisms underlying tissue toxicity remain unknown. We hypothesized that LC induces endothelial dysfunction in non-AL human microvasculature and apoptotic injury in hum...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Migrino, Raymond Q., Truran, Seth, Gutterman, David D., Franco, Daniel A., Bright, Megan, Schlundt, Brittany, Timmons, Mitchell, Motta, Angelica, Phillips, Shane A., Hari, Parameswaran
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Vascular Biology and Microcirculation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233808/
https://ncbi.nlm.nih.gov/pubmed/21963839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00503.2011
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge