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Antagonism of phencyclidine action by metaphit in rat cerebellar Purkinje neurons: an electrophysiological study.

Metaphit (1-[1-(3-isothiocyanatophenyl)-cyclohexyl]piperidine), a derivative of the psychotomimetic drug phencyclidine (PCP), is postulated to bind irreversibly to PCP receptors. We examined here the electrophysiological interactions of metaphit with PCP in rat cerebellar cortex, since a specific ef...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Y, Palmer, M, Freedman, R, Hoffer, B, Mattson, M V, Lessor, R A, Rice, K C, Jacobson, A E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323372/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458231/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.8.2724
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