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Expression of the three influenza virus polymerase proteins in a single cell allows growth complementation of viral mutants.

Transformed cell lines derived from murine C127 cells were constructed that express the influenza virus RNA-dependent RNA polymerase proteins (PA, PB1, and PB2). Cell lines that express only one or all three of the proteins were tested for their ability to complement temperature-sensitive viral muta...

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Библиографические подробности
Опубликовано в::Proc Natl Acad Sci U S A
Главные авторы: Krystal, M, Li, R, Lyles, D, Pavlakis, G, Palese, P
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1986
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3010315/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.8.2709
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