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Impact of the Lectin Chaperone Calnexin on the Stress Response, Virulence and Proteolytic Secretome of the Fungal Pathogen Aspergillus fumigatus

Calnexin is a membrane-bound lectin chaperone in the endoplasmic reticulum (ER) that is part of a quality control system that promotes the accurate folding of glycoproteins entering the secretory pathway. We have previously shown that ER homeostasis is important for virulence of the human fungal pat...

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Détails bibliographiques
Auteurs principaux: Powers-Fletcher, Margaret V., Jambunathan, Kalyani, Brewer, Jordan L., Krishnan, Karthik, Feng, Xizhi, Galande, Amit K., Askew, David S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233604/
https://ncbi.nlm.nih.gov/pubmed/22163332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028865
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