Redistribution of DAT/α-Synuclein Complexes Visualized by “In Situ” Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease

Alpha-synuclein, the major component of Lewy bodies, is thought to play a central role in the onset of synaptic dysfunctions in Parkinson's disease (PD). In particular, α-synuclein may affect dopaminergic neuron function as it interacts with a key protein modulating dopamine (DA) content at the...

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Main Authors: Bellucci, Arianna, Navarria, Laura, Falarti, Elisa, Zaltieri, Michela, Bono, Federica, Collo, Ginetta, Grazia, Maria, Missale, Cristina, Spano, PierFranco
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233557/
https://ncbi.nlm.nih.gov/pubmed/22163275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027959
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