Phase III Randomized Trial of Dose Intensive Neoadjuvant Chemotherapy with or Without G-CSF in Locally Advanced Breast Cancer: Long-Term Results

OBJECTIVE. To compare the pathologic complete response (pCR) rate of patients treated with 5-fluorouracil (5-FU), doxorubicin, and cyclophosphamide (FAC) versus dose-intense FAC plus G-CSF in the neoadjuvant setting and to compare the delivered dose intensity, disease-free survival (DFS) and overall...

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Autores principales: Arun, Banu K., Dhinghra, Kapil, Valero, Vicente, Kau, Shu-Wan, Broglio, Kristine, Booser, Daniel, Guerra, Laura, Yin, Guosheng, Walters, Ronald, Sahin, Aysegul, Ibrahim, Nuhad, Buzdar, Aman U., Frye, Debbie, Sneige, Nour, Strom, Eric, Ross, Merrick, Theriault, Richard L., Vadhan-Raj, Saroj, Hortobagyi, Gabriel N.
Formato: Artigo
Lenguaje:Inglês
Publicado: AlphaMed Press 2011
Materias:
Breast Cancer
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233286/
https://ncbi.nlm.nih.gov/pubmed/22042783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0134
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