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Anti-MuSK autoantibodies block binding of collagen Q to MuSK
OBJECTIVE: Muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) accounts for 5%–15% of autoimmune MG. MuSK mediates the agrin-signaling pathway and also anchors the collagenic tail subunit (ColQ) of acetylcholinesterase (AChE). The exact molecular target of MuSK–i...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Lippincott Williams & Wilkins
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233209/ https://ncbi.nlm.nih.gov/pubmed/22013178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318237f660 |
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