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Superresolution Fluorescence Imaging of Mitochondrial Nucleoids Reveals Their Spatial Range, Limits, and Membrane Interaction

A fundamental objective in molecular biology is to understand how DNA is organized in concert with various proteins, RNA, and biological membranes. Mitochondria maintain and express their own DNA (mtDNA), which is arranged within structures called nucleoids. Their functions, dimensions, composition,...

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Detalhes bibliográficos
Main Authors: Brown, Timothy A., Tkachuk, Ariana N., Shtengel, Gleb, Kopek, Benjamin G., Bogenhagen, Daniel F., Hess, Harald F., Clayton, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233019/
https://ncbi.nlm.nih.gov/pubmed/22006021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05694-11
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