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Survival and Differentiation of Mammary Epithelial Cells in Mammary Gland Development Require Nuclear Retention of Id2 Due to RANK Signaling

RANKL plays an essential role in mammary gland development during pregnancy. However, the molecular mechanism by which RANK signaling leads to mammary gland development is largely unknown. We report here that RANKL stimulation induces phosphorylation of Id2 at serine 5, which leads to nuclear retent...

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Detalhes bibliográficos
Main Authors: Kim, Nam-Shik, Kim, Hyoung-Tai, Kwon, Min-Chul, Choi, Suk-Won, Kim, Yoon-Young, Yoon, Ki-Jun, Koo, Bon-Kyoung, Kong, Myung-Phil, Shin, Juhee, Cho, Yunje, Kong, Young-Yun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232922/
https://ncbi.nlm.nih.gov/pubmed/21947283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05646-11
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