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Deletion of One Nucleotide within the Homonucleotide Tract Present in the hsdS Gene Alters the DNA Sequence Specificity of Type I Restriction-Modification System NgoAV

As a result of a frameshift mutation, the hsdS locus of the NgoAV type IC restriction and modification (RM) system comprises two genes, hsdS(NgoAV1) and hsdS(NgoAV2). The specificity subunit, HsdS(NgoAV), the product of the hsdS(NgoAV1) gene, is a naturally truncated form of an archetypal specificit...

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Autori principali: Adamczyk-Poplawska, Monika, Lower, Michal, Piekarowicz, Andrzej
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232900/
https://ncbi.nlm.nih.gov/pubmed/21984785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05672-11
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