An Escherichia coli O157-Specific Engineered Pyocin Prevents and Ameliorates Infection by E. coli O157:H7 in an Animal Model of Diarrheal Disease

AvR2-V10.3 is an engineered R-type pyocin that specifically kills Escherichia coli O157, an enteric pathogen that is a major cause of food-borne diarrheal disease. New therapeutics to counteract E. coli O157 are needed, as currently available antibiotics can exacerbate the consequences of infection....

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Detalhes bibliográficos
Main Authors: Ritchie, Jennifer M., Greenwich, Jennifer L., Davis, Brigid M., Bronson, Roderick T., Gebhart, Dana, Williams, Steven R., Martin, David, Scholl, Dean, Waldor, Matthew K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232761/
https://ncbi.nlm.nih.gov/pubmed/21947394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05031-11
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