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In Vitro Properties of a Listeria monocytogenes Bacteriophage-Resistant Mutant Predict Its Efficacy as a Live Oral Vaccine Strain

A Listeria monocytogenes glcV mutation precludes the binding of certain listerial phages and produces a profound attenuation characterized by the absence of detectable mutants in the livers and spleens of orally inoculated mice. In vitro, we found that the mutant formed plaques on mouse enterocyte m...

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Detalhes bibliográficos
Main Authors: Spears, Patricia A., Suyemoto, M. Mitsu, Hamrick, Terri S., Wolf, Rebecca L., Havell, Edward A., Orndorff, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232665/
https://ncbi.nlm.nih.gov/pubmed/21930759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05700-11
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