An engineered Plasmodium falciparum C-terminal 19-kilodalton merozoite surface protein 1 vaccine candidate induces high levels of interferon-gamma production associated with cellular immune responses to specific peptide sequences in Gambian adults naturally exposed to malaria

The 19-kDa C-terminal region of merozoite surface protein 1 (MSP1(19)), a major blood stage malaria vaccine candidate, is the target of cellular and humoral immune responses in humans naturally infected with Plasmodium falciparum. We have previously described engineered variants of this protein, des...

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Hlavní autoři: Bisseye, C, Yindom, L M, Simporé, J, Morgan, W D, Holder, A A, Ismaili, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2011
Témata:
Translational Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232385/
https://ncbi.nlm.nih.gov/pubmed/22059995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04467.x
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