Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice

We previously demonstrated that allopregnanolone (APα) increased proliferation of neural progenitor cells and reversed neurogenic and cognitive deficits prior to AD pathology (Wang et al., 2005; 2010). Herein, we determined efficacy of APα to restore neural progenitor cell survival and associative l...

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Hauptverfasser: Singh, Chanpreet, Liu, Lifei, Wang, Jun Ming, Irwin, Ronald W., Yao, Jia, Chen, Shuhua, Henry, Sherry, Thompson, Richard F., Brinton, Roberta Diaz
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232295/
https://ncbi.nlm.nih.gov/pubmed/21803451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.06.008
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