MicroRNA-Driven Developmental Remodeling in the Brain Distinguishes Humans from Other Primates

While multiple studies have reported the accelerated evolution of brain gene expression in the human lineage, the mechanisms underlying such changes are unknown. Here, we address this issue from a developmental perspective, by analyzing mRNA and microRNA (miRNA) expression in two brain regions withi...

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Detalles Bibliográficos
Main Authors: Somel, Mehmet, Liu, Xiling, Tang, Lin, Yan, Zheng, Hu, Haiyang, Guo, Song, Jiang, Xi, Zhang, Xiaoyu, Xu, Guohua, Xie, Gangcai, Li, Na, Hu, Yuhui, Chen, Wei, Pääbo, Svante, Khaitovich, Philipp
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232219/
https://ncbi.nlm.nih.gov/pubmed/22162950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001214
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