In vivo bioavailability studies of sumatriptan succinate buccal tablets

BACK GROUND AND THE PURPOSE OF STUDY: Sumatriptan succinate is a Serotonin 5- HT1 receptor agonist, used in treatment of migraine. It is absorbed rapidly but incompletely when given orally and undergoes first-pass metabolism, resulting in a low absolute bioavailability of about 15%. The aim of this...

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Bibliografiske detaljer
Main Authors: Shivanand, K, Raju, SA, Nizamuddin, S, Jayakar, B
Format: Artigo
Sprog:Inglês
Udgivet: Tehran University of Medical Sciences 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232104/
https://ncbi.nlm.nih.gov/pubmed/22615661
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