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Common SNPs explain a large proportion of heritability for human height

Single nucleotide polymorphisms (SNPs) discovered by genome-wide association studies (GWASs) account for only a small fraction of the genetic variation of complex traits in human populations. Where is the remaining heritability? We estimated the proportion of variance for human height explained by 2...

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Detalhes bibliográficos
Main Authors: Yang, Jian, Benyamin, Beben, McEvoy, Brian P, Gordon, Scott, Henders, Anjali K, Nyholt, Dale R, Madden, Pamela A, Heath, Andrew C, Martin, Nicholas G, Montgomery, Grant W, Goddard, Michael E, Visscher, Peter M
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232052/
https://ncbi.nlm.nih.gov/pubmed/20562875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.608
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