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Cooperative effects in differentiation and proliferation between PDGF-BB and matrix derived synthetic peptides in human osteoblasts

BACKGROUND: Enhancing osteogenic capabilities of bone matrix for the treatment of fractures and segmental defects using growth factors is an active area of research. Recently, synthetic peptides like AC- 100, TP508 or p-15 corresponding to biologically active sequences of matrix proteins have been p...

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Main Authors: Vordemvenne, Thomas, Paletta, Jürgen RJ, Hartensuer, Rene, Pap, Thomas, Raschke, Michael J, Ochman, Sabine
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231994/
https://ncbi.nlm.nih.gov/pubmed/22104124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-12-263
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