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Isolation and structure of a C-terminally amidated nonopioid peptide, amidorphin-(8-26), from bovine striatum: a major product of proenkephalin in brain but not in adrenal medulla.

We have isolated and sequenced a C-terminally amidated peptide from bovine striatum. The peptide was purified to homogeneity by adsorption to XAD-2 resins and four different HPLC steps. Amino acid composition analysis and gas-phase sequence analysis revealed identity of this peptide with residues 8-...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Liebisch, D C, Weber, E, Kosicka, B, Gramsch, C, Herz, A, Seizinger, B R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323199/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456613/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.6.1936
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