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DNA fragmentation: manifestation of target cell destruction mediated by cytotoxic T-cell lines, lymphotoxin-secreting helper T-cell clones, and cell-free lymphotoxin-containing supernatant.

A Lyt-2+, trinitrophenyl-specific, lymphotoxin-secreting, cytotoxic T-cell line, PCl 55, mediates the digestion of target cell DNA into discretely sized fragments. This phenomenon manifests itself within 30 min after effector cell encounter as measured by the release of 3H counts from target cells p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Schmid, D S, Tite, J P, Ruddle, N H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323188/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2937063/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.6.1881
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