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Relationships between Liposome Properties, Cell Membrane Binding, Intracellular Processing, and Intracellular Bioavailability

Positive surface charge enhances liposome uptake into cells. Pegylation, used to confer stealth properties to enable in vivo applications of cationic liposomes, compromises internalization. The goal of this study was to determine the quantitative relationships between these two liposome properties (...

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Autors principals: Li, Yinghuan, Wang, Jie, Gao, Yue, Zhu, Jiabi, Wientjes, M. Guillaume, Au, Jessie L.-S.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231863/
https://ncbi.nlm.nih.gov/pubmed/21904966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-011-9298-1
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