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Rearrangements of DNA mediated by terminal transferase.

To assess the involvement of terminal transferase in generating immunoglobulin diversity, the mutagenic potential of this enzyme has been measured. The frequency of single base substitutions during copying of phi X174 DNA by DNA polymerase beta is increased by, at most, 3-fold upon the addition of t...

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Detalhes bibliográficos
Main Authors: Kunkel, T A, Gopinathan, K P, Dube, D K, Snow, E T, Loeb, L A
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC323185/
https://ncbi.nlm.nih.gov/pubmed/2937062
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