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Multiplex Sequencing of Seven Ocular Herpes Simplex Virus Type-1 Genomes: Phylogeny, Sequence Variability, and SNP Distribution

PURPOSE. Little is known about the role of sequence variation in the pathology of HSV-1 keratitis virus. The goal was to show that a multiplex, high-throughput genome-sequencing approach is feasible for simultaneously sequencing seven HSV-1 ocular strains. METHODS. A genome sequencer was used to seq...

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Hlavní autoři: Kolb, Aaron W., Adams, Marie, Cabot, Eric L., Craven, Mark, Brandt, Curtis R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Association for Research in Vision and Ophthalmology, Inc. 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231845/
https://ncbi.nlm.nih.gov/pubmed/22016062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7812
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