The Structure of Ca(2+) Sensor Case16 Reveals the Mechanism of Reaction to Low Ca(2+) Concentrations

Here we report the first crystal structure of a high-contrast genetically encoded circularly permuted green fluorescent protein (cpGFP)-based Ca(2+) sensor, Case16, in the presence of a low Ca(2+) concentration. The structure reveals the positioning of the chromophore within Case16 at the first stag...

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Auteurs principaux: Leder, Lukas, Stark, Wilhelm, Freuler, Felix, Marsh, May, Meyerhofer, Marco, Stettler, Thomas, Mayr, Lorenz M., Britanova, Olga V., Strukova, Lydia A., Chudakov, Dmitriy M., Souslova, Ekaterina A.
Format: Artigo
Langue:Inglês
Publié: Molecular Diversity Preservation International (MDPI) 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231237/
https://ncbi.nlm.nih.gov/pubmed/22163646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s100908143
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