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Use of a Multiplexed CMOS Microarray to Optimize and Compare Oligonucleotide Binding to DNA Probes Synthesized or Immobilized on Individual Electrodes

The CombiMatrix microarray with 12,544 electrodes supports in situ electrochemical synthesis of user-defined DNA probes. As an alternative, we immobilized commercially synthesized DNA probes on individual electrodes coated with electropolymerized polypyrrole (Ppy). Hybridization was measured using a...

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Detalhes bibliográficos
Main Authors: Maurer, Karl, Yazvenko, Nina, Wilmoth, Jodi, Cooper, John, Lyon, Wanda, Danley, David
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231185/
https://ncbi.nlm.nih.gov/pubmed/22163607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s100807371
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