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Hybrid hybridoma producing a bispecific monoclonal antibody that can focus effector T-cell activity.

Previous studies have shown that heteroconjugates of monoclonal antibodies in which one of the component antibodies is directed at the T-cell receptor and the other is directed against any chosen site can focus effector T cells to function at the targeted site. We report here the production of a hyb...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Staerz, U D, Bevan, M J
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2869486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.5.1453
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