Role of the inflammatory protein serine protease inhibitor Kazal in preventing cytolytic granule granzyme A-mediated apoptosis

Serine protease inhibitor Kazal (SPIK) is an inflammatory protein whose levels are elevated in numerous cancers. However, the role of this protein in cancer development is unknown. We have recently found that SPIK suppresses serine protease-dependent cell apoptosis. Here, we report that anti-SPIK an...

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Autores principales: Lu, Felix, Lamontagne, Jason, Sun, Angela, Pinkerton, Mark, Block, Timothy, Lu, Xuanyong
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2011
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230794/
https://ncbi.nlm.nih.gov/pubmed/22043941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03498.x
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