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Two-Dimensional Target Decoy Strategy for Shotgun Proteomics

The target-decoy approach to estimating and controlling false discovery rate (FDR) has become a de facto standard in shotgun proteomics, and it has been applied at both the peptide-to-spectrum match (PSM) and protein levels. Current bioinformatics methods control either the PSM- or the protein-level...

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Detalhes bibliográficos
Main Authors: Bern, Marshall W., Kil, Yong J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230778/
https://ncbi.nlm.nih.gov/pubmed/22010998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200780j
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