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Interaction of Tamoxifen and noise induced damage to the cochlea

Tamoxifen has been used extensively in the treatment of breast cancer and other neoplasms. In addition to its well-known action on estrogen receptors it is also known to acutely block chloride channels that participate in cell volume regulation. Tamoxifen’s role in preventing cochlear outer hair cel...

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Detalhes bibliográficos
Main Authors: Pillai, Jagan A, Siegel, Jonathan H
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230769/
https://ncbi.nlm.nih.gov/pubmed/21907781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2011.08.012
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