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Induction of regulatory Tr1 cells and inhibition of T(H)17 cells by IL-27
Accumulating evidence indicates that IL-27, a member of the IL-12 family of cytokines, alleviates the severity of autoimmune diseases in both mice and men. The IL-27-induced activation of Signal transducer and activator of transcription (Stat)1 and Stat3 promotes the generation of IL-10-producing ty...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230686/ https://ncbi.nlm.nih.gov/pubmed/21893418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2011.08.003 |
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