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Substrate Adhesion Regulates Sealing Zone Architecture and Dynamics in Cultured Osteoclasts

The bone-degrading activity of osteoclasts depends on the formation of a cytoskeletal-adhesive super-structure known as the sealing zone (SZ). The SZ is a dynamic structure, consisting of a condensed array of podosomes, the elementary adhesion-mediating structures of osteoclasts, interconnected by F...

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Detalhes bibliográficos
Main Authors: Anderegg, Fabian, Geblinger, Dafna, Horvath, Peter, Charnley, Mirren, Textor, Marcus, Addadi, Lia, Geiger, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230604/
https://ncbi.nlm.nih.gov/pubmed/22162778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028583
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