PTEN Modulates miR-21 Processing via RNA-Regulatory Protein RNH1

Aberrant miR-21 expression is closely associated with cell proliferation, anti-apoptosis, migration, invasion, and metastasis in various cancers. However, the regulatory mechanism of miR-21 biogenesis is largely unknown. Here, we demonstrated that the tumor suppressor PTEN negatively regulates the e...

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Detalhes bibliográficos
Main Authors: Kim, Youn-Jae, Park, Se-Jeong, Choi, Eun Young, Kim, Sol, Kwak, Hee Jin, Yoo, Byong Chul, Yoo, Heon, Lee, Seung-Hoon, Kim, Daesoo, Park, Jong Bae, Kim, Jong Heon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230587/
https://ncbi.nlm.nih.gov/pubmed/22162762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028308
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