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Polycomb group genes are targets of aberrant DNA methylation in renal cell carcinoma

The combined effects of genetic and epigenetic aberrations are well recognized as causal in tumorigenesis. Here, we defined profiles of DNA methylation in primary renal cell carcinomas (RCC) and assessed the association of these profiles with the expression of genes required for the establishment an...

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Autori principali: Avissar-Whiting, Michele, Koestler, Devin C, Houseman, E Andres, Christensen, Brock C, Kelsey, Karl T, Marsit, Carmen J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230543/
https://ncbi.nlm.nih.gov/pubmed/21610323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.6.16158
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