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A novel nuclear miRNA mediated modulation of a non-coding antisense RNA and its cognate sense coding mRNA
MicroRNAs control gene expression by inhibition of protein translation and by mRNA degradation. Now, a new mode of action for miRNAs is reported: nuclear-localized miRNAs target non-coding antisense transcripts via the Ago2 slicer complex.
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230383/ https://ncbi.nlm.nih.gov/pubmed/22048334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.373 |
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