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Lipid droplet meets a mitochondrial protein to regulate adipocyte lipolysis
Optic Atrophy 1 (OPA1) is well known as a regulator of mitochondrial dynamics. Now, a new function of OPA1 is uncovered: recruiting protein kinase A to lipid droplets, thereby controlling the activity of perilipin, and hence lipolysis.
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230382/ https://ncbi.nlm.nih.gov/pubmed/22048333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.371 |
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